DBTMEE
Database of Transcriptome in Mouse Early Embryos


Gene Search:

DBTMEE:0002373
GeneAkt1
SynonymsAkt
PKB
PKB/Akt
PKBalpha
Desc.thymoma viral proto-oncogene 1
LocusNM_009652 chr12:113892032-113912487(-)
NM_001165894 chr12:113892032-113912487(-)
DB links


Entrez 11651
MGI 87986
Ensembl ENSMUSG00000001729
Vega OTTMUSG00000020941
Featureprotein-coding
GO(BP)
  •   78 Terms
      protein import into nucleus, translocation (GO:0000060)
      osteoblast differentiation (GO:0001649)
      maternal placenta development (GO:0001893)
      positive regulation of protein phosphorylation (GO:0001934)
      carbohydrate metabolic process (GO:0005975)
      glycogen metabolic process (GO:0005977)
      glycogen biosynthetic process (GO:0005978)
      regulation of glycogen biosynthetic process (GO:0005979)
      glucose metabolic process (GO:0006006)
      translation (GO:0006412)
      regulation of translation (GO:0006417)
      protein phosphorylation (GO:0006468)
      negative regulation of protein kinase activity (GO:0006469)
      transport (GO:0006810)
      apoptotic process (GO:0006915)
      activation-induced cell death of T cells (GO:0006924)
      inflammatory response (GO:0006954)
      cytoskeleton organization (GO:0007010)
      signal transduction (GO:0007165)
      multicellular organismal development (GO:0007275)
      germ cell development (GO:0007281)
      nervous system development (GO:0007399)
      aging (GO:0007568)
      insulin receptor signaling pathway (GO:0008286)
      apoptotic mitochondrial changes (GO:0008637)
      carbohydrate transport (GO:0008643)
      response to hormone stimulus (GO:0009725)
      negative regulation of plasma membrane long-chain fatty acid transport (GO:0010748)
      positive regulation of sodium ion transport (GO:0010765)
      positive regulation of glucose metabolic process (GO:0010907)
      regulation of neuron projection development (GO:0010975)
      glucose transport (GO:0015758)
      phosphorylation (GO:0016310)
      protein ubiquitination (GO:0016567)
      peptidyl-serine phosphorylation (GO:0018105)
      cell projection organization (GO:0030030)
      protein catabolic process (GO:0030163)
      positive regulation of cell growth (GO:0030307)
      regulation of cell migration (GO:0030334)
      positive regulation of cyclin-dependent protein kinase activity involved in G1/S (GO:0031659)
      negative regulation of fatty acid beta-oxidation (GO:0031999)
      response to food (GO:0032094)
      positive regulation of cellular protein metabolic process (GO:0032270)
      peripheral nervous system myelin maintenance (GO:0032287)
      positive regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032436)
      cellular response to insulin stimulus (GO:0032869)
      regulation of protein localization (GO:0032880)
      positive regulation of peptidyl-serine phosphorylation (GO:0033138)
      response to fluid shear stress (GO:0034405)
      intracellular signal transduction (GO:0035556)
      glucose homeostasis (GO:0042593)
      anagen (GO:0042640)
      positive regulation of apoptotic process (GO:0043065)
      negative regulation of apoptotic process (GO:0043066)
      negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043154)
      protein kinase B signaling cascade (GO:0043491)
      positive regulation of blood vessel endothelial cell migration (GO:0043536)
      positive regulation of nitric oxide biosynthetic process (GO:0045429)
      positive regulation of fat cell differentiation (GO:0045600)
      positive regulation of glycogen biosynthetic process (GO:0045725)
      negative regulation of cell size (GO:0045792)
      positive regulation of vasoconstriction (GO:0045907)
      positive regulation of transcription from RNA polymerase II promoter (GO:0045944)
      positive regulation of glucose import (GO:0046326)
      negative regulation of JNK cascade (GO:0046329)
      positive regulation of lipid biosynthetic process (GO:0046889)
      insulin-like growth factor receptor signaling pathway (GO:0048009)
      positive regulation of nitric-oxide synthase activity (GO:0051000)
      positive regulation of sequence-specific DNA binding transcription factor activity (GO:0051091)
      striated muscle cell differentiation (GO:0051146)
      glycogen cell differentiation involved in embryonic placenta development (GO:0060709)
      labyrinthine layer blood vessel development (GO:0060716)
      response to UV-A (GO:0070141)
      cellular response to growth factor stimulus (GO:0071363)
      cellular response to epidermal growth factor stimulus (GO:0071364)
      cellular response to hypoxia (GO:0071456)
      positive regulation of establishment of protein localization to plasma membrane (GO:0090004)
      negative regulation of release of cytochrome c from mitochondria (GO:0090201)
GO(MF)
GO(CC)
KEGG
Ver2_FPKM
DBTMEEGeneRefSeqEntrezSPR_FPKMOo_FPKM1C_FPKM2C_FPKM4C_FPKMESC_FPKMMEF_FPKMp1C_FPKMp4C_FPKMiPSC_FPKM
2002257
(v2.0)
Akt1NM_001165894,NM_00965211651
95.351563.1784114.41942.969745.342918.731364.3128151.04545.761719.4554
SOLiD_Cluster_gene_guided
DBTMEEGeneEntrezClusterCorrelation
0002373
(v1.0)
Akt111651
Minor ZGA0.97691
SPR_Histone_Erkek_+-5KfromTSS
DBTMEEGeneEntrezH3.3_1
(ChIP/Input)
H3.3_1
(Enrich; log2)
H3.3_2
(ChIP/Input)
H3.3_2
(Enrich; log2)
H3K4me3_1
(ChIP/Input)
H3K4me3_1
(Enrich; log2)
H3K4me3_2
(ChIP/Input)
H3K4me3_2
(Enrich; log2)
H3K27me3_1
(ChIP/Input)
H3K27me3_1
(Enrich; log2)
H3K27me3_2
(ChIP/Input)
H3K27me3_2
(Enrich; log2)
2002257
(v2.0)
Akt111651
914/5310.2702401/531-0.5201145/5311.7057395/5310.901341/531-1.6137512/531-0.6504
SPR_Histone_Erkek_+-2KfromTSS
DBTMEEGeneEntrezH3.3_1
(ChIP/Input)
H3.3_1
(Enrich; log2)
H3.3_2
(ChIP/Input)
H3.3_2
(Enrich; log2)
H3K4me3_1
(ChIP/Input)
H3K4me3_1
(Enrich; log2)
H3K4me3_2
(ChIP/Input)
H3K4me3_2
(Enrich; log2)
H3K27me3_1
(ChIP/Input)
H3K27me3_1
(Enrich; log2)
H3K27me3_2
(ChIP/Input)
H3K27me3_2
(Enrich; log2)
2002257
(v2.0)
Akt111651
353/1830.433150/183-0.400684/1832.4021235/1831.678527/183-0.683257/183-0.1088
SPR_Methy_Kobayashi_+-5KfromTSS
DBTMEEGeneEntrezTotal_mC_levelsNumber_of_mCsAveraged_Methylation_level(%)
2002257
(v2.0)
Akt111651
76.251118641
SPR_Methy_Kobayashi_+-2KfromTSS
DBTMEEGeneEntrezTotal_mC_levelsNumber_of_mCsAveraged_Methylation_level(%)
2002257
(v2.0)
Akt111651
13.33427817.1
SOLiD_Oo-4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM1C_FPKM2C_FPKM4C_FPKMMEF_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
65.695879.513532.018331.42645.857
SOLiD_NMNR_Oo-4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM1C_FPKM2C_FPKM4C_FPKMMEF_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
237.619434.65146.275145.361146.525
SOLiD_Illumina_Oo-1C-Sperm_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKMSPR_FPKM1C_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
68.69134.868186.7509
SOLiD_Partheno1C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM1C_FPKMp1C_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
67.049278.7151111.955
SOLiD_NMNR_Partheno1C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrez1C_FPKMp1C_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
1008.62964.921
SOLiD_Illumina_Oo-p1C-Sperm_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKMSPR_FPKMp1C_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
68.730934.3906122.789
SOLiD_Partheno4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrez2C_FPKM4C_FPKMp4C_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
29.643930.343131.7746
SOLiD_NMNR_Partheno4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrez4C_FPKMp4C_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
136.816139.692
Illumina_Oo-2C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM2C_FPKM
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
23.424729.8971
SOLiD_SC_Oo_REPLICA_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_1_1Oo_2_1
0002373
(v1.0)
Akt1NM_001165894,NM_00965211651
122.0791.4608
NIA60mer
DBTMEEArray Feature NumberOligo Parent CloneUnigeneGeneEntrezU_ClusterNAP_ClusterGene_U/NAPTIGRSwissProtESTOo1C2C4C8CMorulaBlastocyst
0002373
(v1.0)
5145M94335.1Akt111651
U034387NAP011029-001Akt1;TC847897P31750U,F,23.04723.00052.95062.84442.78632.83272.8113
0002373
(v1.0)
6195H3020C06-3Mm.6645Akt111651
U034387NAP011029-001Akt1;TC847897P31750U,F,23.06013.03932.89942.65292.29542.55912.4971
MOE430
DBTMEEProbe_IDUnigeneGeneRefSeqEntrezOo1C2C8CBlastocyst
0002373
(v1.0)
1416657_atMm.6645Akt1NM_009652.3,NM_001165894.111651
259.375458.15303.05145.775143.4
Agilent44K
DBTMEEProbe_IDGeneAcc.EntrezOo1_x-foldOo1_p-value (t-test)Oo1_FlagOo2_x-foldOo2_p-value (t-test)Oo2_Flag
0002373
(v1.0)
A_51_P237553Akt1NM_00965211651
1 (0.916 to 1.074)1P1.187 (1.07 to 1.289)0.000749P
0002373
(v1.0)
A_52_P418014Akt1NM_00965211651
11P0.6490.233P
Proteome N/A