DBTMEE:2014617
| Gene | Nr1h2 |
| Synonyms | LXRB
LXRbeta
RIP15
Unr2 |
| Description | nuclear receptor subfamily 1, group H, member 2 |
| Locus | NM_009473 UCSC: chr7:51804986-51809335(-) OLP: chr7:51804986-51809335(-)
NM_001285518 UCSC: chr7:51804986-51809335(-) OLP: chr7:51804986-51809335(-)
NM_001285517 UCSC: chr7:51804986-51809335(-) OLP: chr7:51804986-51809335(-)
NM_001285519 UCSC: chr7:51804986-51809335(-) OLP: chr7:51804986-51809335(-)
|
| DB links |
Entrez 22260
MGI 1352463
Ensembl ENSMUSG00000060601
Vega OTTMUSG00000023074
|
| Feature | protein-coding |
| GO_BP |
-
 30 Terms
negative regulation of transcription from RNA polymerase II promoter (GO:0000122)
transcription, DNA-templated (GO:0006351)
regulation of transcription, DNA-templated (GO:0006355)
regulation of transcription from RNA polymerase II promoter (GO:0006357)
transcription from RNA polymerase II promoter (GO:0006366)
positive regulation of gene expression (GO:0010628)
negative regulation of gene expression (GO:0010629)
positive regulation of triglyceride biosynthetic process (GO:0010867)
positive regulation of cholesterol efflux (GO:0010875)
positive regulation of lipid storage (GO:0010884)
negative regulation of cholesterol storage (GO:0010887)
intracellular receptor signaling pathway (GO:0030522)
positive regulation of cellular protein metabolic process (GO:0032270)
negative regulation of lipid transport (GO:0032369)
positive regulation of cholesterol transport (GO:0032376)
cholesterol homeostasis (GO:0042632)
steroid hormone mediated signaling pathway (GO:0043401)
cellular lipid metabolic process (GO:0044255)
positive regulation of fatty acid biosynthetic process (GO:0045723)
negative regulation of proteolysis (GO:0045861)
negative regulation of transcription, DNA-templated (GO:0045892)
positive regulation of transcription from RNA polymerase II promoter (GO:0045944)
retinoic acid receptor signaling pathway (GO:0048384)
negative regulation of pinocytosis (GO:0048550)
positive regulation of lipoprotein lipase activity (GO:0051006)
lipid homeostasis (GO:0055088)
positive regulation of high-density lipoprotein particle assembly (GO:0090108)
positive regulation of pancreatic juice secretion (GO:0090187)
positive regulation of secretion of lysosomal enzymes (GO:0090340)
regulation of cholesterol homeostasis (GO:2000188)
|
| GO_MF |
-
14 Terms
RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978)
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (GO:0001077)
sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity (GO:0001133)
DNA binding (GO:0003677)
sequence-specific DNA binding transcription factor activity (GO:0003700)
steroid hormone receptor activity (GO:0003707)
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity (GO:0004879)
protein binding (GO:0005515)
zinc ion binding (GO:0008270)
apolipoprotein A-I receptor binding (GO:0034191)
sequence-specific DNA binding (GO:0043565)
metal ion binding (GO:0046872)
retinoid X receptor binding (GO:0046965)
ATPase binding (GO:0051117)
|
| GO_CC |
-
2 Terms
|
| KEGG | |
| Ver2_FPKM |
| DBTMEE | Gene | RefSeq | Entrez | SPR_FPKM | Oo_FPKM | 1C_FPKM | 2C_FPKM | 4C_FPKM | ESC_FPKM | MEF_FPKM | p1C_FPKM | p4C_FPKM | iPSC_FPKM |
|---|
2014617
(v2.0) | Nr1h2 | NM_001285517,NM_001285518,NM_001285519,NM_009473 | 22260
| 32.3434 | 13.4653 | 9.21693 | 19.5994 | 31.7514 | 40.9054 | 9.02099 | 17.4609 | 36.9426 | 53.413 |
|
| SPR_Histone_Erkek_5KaroundTSS |
| DBTMEE | Gene | Entrez | H3.3_1_ChIP/Input | H3.3_1(Enrich; log2) | H3.3_2_ChIP/Input | H3.3_2(Enrich; log2) | H3K4me3_1_ChIP/Input | H3K4me3_1(Enrich; log2) | H3K4me3_2_ChIP/Input | H3K4me3_2(Enrich; log2) | H3K27me3_1_ChIP/Input | H3K27me3_1(Enrich; log2) | H3K27me3_2_ChIP/Input | H3K27me3_2(Enrich; log2) |
|---|
2014617
(v2.0) | Nr1h2 | 22260
| 764/508 | 0.0758 | 322/508 | -0.772 | 68/508 | 0.6869 | 246/508 | 0.2838 | 31/508 | -1.9427 | 379/508 | -1.0191 |
|
| SPR_Histone_Erkek_2KaroundTSS |
| DBTMEE | Gene | Entrez | H3.3_1_ChIP/Input | H3.3_1(Enrich; log2) | H3.3_2_ChIP/Input | H3.3_2(Enrich; log2) | H3K4me3_1_ChIP/Input | H3K4me3_1(Enrich; log2) | H3K4me3_2_ChIP/Input | H3K4me3_2(Enrich; log2) | H3K27me3_1_ChIP/Input | H3K27me3_1(Enrich; log2) | H3K27me3_2_ChIP/Input | H3K27me3_2(Enrich; log2) |
|---|
2014617
(v2.0) | Nr1h2 | 22260
| 314/208 | 0.081 | 128/208 | -0.8114 | 57/208 | 1.6768 | 214/208 | 1.3617 | 4/208 | -3.3493 | 86/208 | -1.8553 |
|
| SPR_Methy_Kobayashi_5KaroundTSS |
| DBTMEE | Gene | Entrez | Total_mC_levels | Number_of_mCs | Averaged_Methylation_level |
|---|
2014617
(v2.0) | Nr1h2 | 22260
| 135.432 | 214 | 63.29 |
|
| SPR_Methy_Kobayashi_2KaroundTSS |
| DBTMEE | Gene | Entrez | Total_mC_levels | Number_of_mCs | Averaged_Methylation_level |
|---|
2014617
(v2.0) | Nr1h2 | 22260
| 42.0002 | 107 | 39.25 |
|
| SOLiD_OocyteTo4C_FPKM_gene_guided |
N/A |
| SOLiD_Illumina_Oo_1C_Sperm_FPKM_gene_guided |
N/A |
| SOLiD_Partheno1C_FPKM_gene_guided |
N/A |
| SOLiD_Illumina_Oo_p1C_Sperm_FPKM_gene_guided |
N/A |
| SOLiD_Partheno4C_FPKM_gene_guided |
N/A |
| Illumina_Oo_2C_FPKM_gene_guided |
N/A |
| SOLiD_SC_Oo_REPLICA_FPKM_gene_guided |
N/A |
| NIA60mer |
| DBTMEE | Array_Feature_Number | Oligo_Parent_Clone | Unigene | Gene | Entrez | U_Cluster | NAP_Cluster | Gene_U/NAP | TIGR | SwissProt | EST | Oo | 1C | 2C | 4C | 8C | Morula | Blastocyst |
|---|
0014160
(v1.0) | 7993 | H3057H11-3 | Mm.968 | Nr1h2 | 22260
| U041431 | NAP030699-1 | Nr1h2; | TC799470,TC799469 | Q60644 | U,F | 3.2403 | 3.1305 | 3.1618 | 3.0696 | 3.7488 | 3.3353 | 3.5625 |
|
| MOE430 |
N/A |
| Agilent44K |
N/A |
| Proteome |
N/A |
