Gene | Gclc |
Synonyms | D9Wsu168e gamma GCS-HS GLCL-H Glclc |
Description | glutamate-cysteine ligase, catalytic subunit |
Locus | NM_010295 UCSC: chr9:77602342-77642296(+) OLP: chr9:77602342-77642296(+)
|
DB links |

Entrez 14629 MGI 104990 Ensembl ENSMUSG00000032350 Vega OTTMUSG00000021059
|
Feature | protein-coding |
GO_BP |
-
 21 Terms
cysteine metabolic process (GO:0006534)
glutamate metabolic process (GO:0006536)
glutathione metabolic process (GO:0006749)
glutathione biosynthetic process (GO:0006750)
response to oxidative stress (GO:0006979)
apoptotic mitochondrial changes (GO:0008637)
response to heat (GO:0009408)
response to xenobiotic stimulus (GO:0009410)
response to hormone (GO:0009725)
L-ascorbic acid metabolic process (GO:0019852)
negative regulation of protein ubiquitination (GO:0031397)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032436)
negative regulation of apoptotic process (GO:0043066)
negative regulation of neuron apoptotic process (GO:0043524)
cell redox homeostasis (GO:0045454)
negative regulation of transcription, DNA-templated (GO:0045892)
response to arsenic-containing substance (GO:0046685)
regulation of blood vessel size (GO:0050880)
response to nitrosative stress (GO:0051409)
regulation of mitochondrial depolarization (GO:0051900)
negative regulation of extrinsic apoptotic signaling pathway (GO:2001237)
|
GO_MF |
-
 9 Terms
|
GO_CC |
-
 2 Terms
|
KEGG |
-
 2 Terms
|
Ver2_FPKM |
DBTMEE | Gene | RefSeq | Entrez | SPR_FPKM | Oo_FPKM | 1C_FPKM | 2C_FPKM | 4C_FPKM | ESC_FPKM | MEF_FPKM | p1C_FPKM | p4C_FPKM | iPSC_FPKM |
2007862 (v2.0) | Gclc | NM_010295 | 14629
| 14.8785 | 8.55872 | 3.64806 | 46.7429 | 9.76529 | 14.4927 | 14.5672 | 1.75035 | 10.7997 | 18.1614 |
|
SPR_Histone_Erkek_5KaroundTSS |
Enrichment of Histone Variant and Modification (+/- 5Kb from TSS)
DBTMEE | Gene | Entrez | H3.3_1_ChIP/Input | H3.3_1(Enrich; log2) | H3.3_2_ChIP/Input | H3.3_2(Enrich; log2) | H3K4me3_1_ChIP/Input | H3K4me3_1(Enrich; log2) | H3K4me3_2_ChIP/Input | H3K4me3_2(Enrich; log2) | H3K27me3_1_ChIP/Input | H3K27me3_1(Enrich; log2) | H3K27me3_2_ChIP/Input | H3K27me3_2(Enrich; log2) |
2007862 (v2.0) | Gclc | 14629
| 725/472 | 0.1062 | 448/472 | -0.1911 | 171/472 | 2.1081 | 482/472 | 1.3568 | 32/472 | -1.7931 | 224/472 | -1.668 |
|
SPR_Histone_Erkek_2KaroundTSS |
Enrichment of Histone Variant and Modification (+/- 2Kb from TSS)
DBTMEE | Gene | Entrez | H3.3_1_ChIP/Input | H3.3_1(Enrich; log2) | H3.3_2_ChIP/Input | H3.3_2(Enrich; log2) | H3K4me3_1_ChIP/Input | H3K4me3_1(Enrich; log2) | H3K4me3_2_ChIP/Input | H3K4me3_2(Enrich; log2) | H3K27me3_1_ChIP/Input | H3K27me3_1(Enrich; log2) | H3K27me3_2_ChIP/Input | H3K27me3_2(Enrich; log2) |
2007862 (v2.0) | Gclc | 14629
| 293/186 | 0.1421 | 168/186 | -0.2615 | 73/186 | 2.1802 | 226/186 | 1.5993 | 16/186 | -1.4258 | 102/186 | -1.4525 |
|
SPR_Methy_Kobayashi_5KaroundTSS |
DBTMEE | Gene | Entrez | Total_mC_levels | Number_of_mCs | Averaged_Methylation_level |
2007862 (v2.0) | Gclc | 14629
| 63.4758 | 145 | 43.78 |
|
SPR_Methy_Kobayashi_2KaroundTSS |
DBTMEE | Gene | Entrez | Total_mC_levels | Number_of_mCs | Averaged_Methylation_level |
2007862 (v2.0) | Gclc | 14629
| 25.597 | 58 | 44.13 |
|
SOLiD_OocyteTo4C_FPKM_gene_guided |
N/A |
SOLiD_Illumina_Oo_1C_Sperm_FPKM_gene_guided |
N/A |
SOLiD_Partheno1C_FPKM_gene_guided |
N/A |
SOLiD_Illumina_Oo_p1C_Sperm_FPKM_gene_guided |
N/A |
SOLiD_Partheno4C_FPKM_gene_guided |
N/A |
Illumina_Oo_2C_FPKM_gene_guided |
N/A |
SOLiD_SC_Oo_REPLICA_FPKM_gene_guided |
N/A |
NIA60mer |
DBTMEE | Array_Feature_Number | Oligo_Parent_Clone | Unigene | Gene | Entrez | U_Cluster | NAP_Cluster | Gene_U/NAP | TIGR | SwissProt | EST | Oo | 1C | 2C | 4C | 8C | Morula | Blastocyst |
0007931 (v1.0) | 5560 | H3002G11-3 | Mm.4368 | Gclc | 14629
| U010769 | NAP009737-001 | Gclc; | TC869395 | P97494 | U,F,2 | 3.3179 | 3.1669 | 3.4079 | 3.6066 | 3.0076 | 3.2374 | 3.3416 |
|
MOE430 |
N/A |
Agilent44K |
N/A |
Proteome |
N/A |