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DB status: OK
Last modified: 2024/03/24

Gene Search:

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DBTMEE:2004636

Gene	Chuk
Synonyms	Chuk1 IkappaB kinase alpha IKK 1 IKK alpha IKK-1 IKK-alpha IKK[a] IKK1 IKKalpha
Description	conserved helix-loop-helix ubiquitous kinase
Locus	NM_007700 UCSC: chr19:44147824-44181967(-) OLP: chr19:44147824-44181967(-) NM_001162410 UCSC: chr19:44147824-44181967(-) OLP: chr19:44147824-44181967(-)
DB links	Entrez 12675 MGI 99484 Ensembl ENSMUSG00000025199 Vega OTTMUSG00000029724
Feature	protein-coding
GO_BP	17 Terms morphogenesis of an epithelial sheet (GO:0002011) protein phosphorylation (GO:0006468) I-kappaB phosphorylation (GO:0007252) Rho protein signal transduction (GO:0007266) lactation (GO:0007595) response to organic substance (GO:0010033) phosphorylation (GO:0016310) signal transduction by phosphorylation (GO:0023014) osteoclast differentiation (GO:0030316) response to lipopolysaccharide (GO:0032496) mammary gland epithelial cell proliferation (GO:0033598) odontogenesis of dentin-containing tooth (GO:0042475) positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123) positive regulation of transcription from RNA polymerase II promoter (GO:0045944) striated muscle cell differentiation (GO:0051146) mammary gland alveolus development (GO:0060749) cellular response to tumor necrosis factor (GO:0071356)
GO_MF	13 Terms nucleotide binding (GO:0000166) protein kinase activity (GO:0004672) protein serine/threonine kinase activity (GO:0004674) receptor signaling protein serine/threonine kinase activity (GO:0004702) protein binding (GO:0005515) ATP binding (GO:0005524) IkappaB kinase activity (GO:0008384) kinase activity (GO:0016301) transferase activity (GO:0016740) transferase activity, transferring phosphorus-containing groups (GO:0016772) protein homodimerization activity (GO:0042803) protein heterodimerization activity (GO:0046982) scaffold protein binding (GO:0097110)
GO_CC	7 Terms nucleus (GO:0005634) cytoplasm (GO:0005737) cytosol (GO:0005829) IkappaB kinase complex (GO:0008385) cytoplasmic side of plasma membrane (GO:0009898) CD40 receptor complex (GO:0035631) intracellular membrane-bounded organelle (GO:0043231)
KEGG	21 Terms MAPK signaling pathway (mmu04010) Chemokine signaling pathway (mmu04062) Apoptosis (mmu04210) Osteoclast differentiation (mmu04380) Toll-like receptor signaling pathway (mmu04620) NOD-like receptor signaling pathway (mmu04621) RIG-I-like receptor signaling pathway (mmu04622) Cytosolic DNA-sensing pathway (mmu04623) T cell receptor signaling pathway (mmu04660) B cell receptor signaling pathway (mmu04662) Adipocytokine signaling pathway (mmu04920) Chagas disease (American trypanosomiasis) (mmu05142) Toxoplasmosis (mmu05145) Hepatitis C (mmu05160) Measles (mmu05162) Pathways in cancer (mmu05200) Pancreatic cancer (mmu05212) Prostate cancer (mmu05215) Chronic myeloid leukemia (mmu05220) Acute myeloid leukemia (mmu05221) Small cell lung cancer (mmu05222)
Ver2_FPKM	DBTMEE Gene RefSeq Entrez SPR_FPKM Oo_FPKM 1C_FPKM 2C_FPKM 4C_FPKM ESC_FPKM MEF_FPKM p1C_FPKM p4C_FPKM iPSC_FPKM 2004636 (v2.0) Chuk NM_001162410,NM_007700 12675 6.96254 6.10111 5.54808 20.1527 15.4933 9.48083 15.1209 4.1951 15.5955 9.17157
SPR_Histone_Erkek_5KaroundTSS	DBTMEE Gene Entrez H3.3_1_ChIP/Input H3.3_1(Enrich; log2) H3.3_2_ChIP/Input H3.3_2(Enrich; log2) H3K4me3_1_ChIP/Input H3K4me3_1(Enrich; log2) H3K4me3_2_ChIP/Input H3K4me3_2(Enrich; log2) H3K27me3_1_ChIP/Input H3K27me3_1(Enrich; log2) H3K27me3_2_ChIP/Input H3K27me3_2(Enrich; log2) 2004636 (v2.0) Chuk 12675 679/447 0.0901 452/447 -0.0999 79/447 1.0802 209/447 0.2333 23/447 -2.1748 95/447 -2.814
SPR_Histone_Erkek_2KaroundTSS	DBTMEE Gene Entrez H3.3_1_ChIP/Input H3.3_1(Enrich; log2) H3.3_2_ChIP/Input H3.3_2(Enrich; log2) H3K4me3_1_ChIP/Input H3K4me3_1(Enrich; log2) H3K4me3_2_ChIP/Input H3K4me3_2(Enrich; log2) H3K27me3_1_ChIP/Input H3K27me3_1(Enrich; log2) H3K27me3_2_ChIP/Input H3K27me3_2(Enrich; log2) 2004636 (v2.0) Chuk 12675 304/178 0.258 186/178 -0.0525 76/178 2.297 195/178 1.45 11/178 -1.8663 45/178 -2.5435
SPR_Methy_Kobayashi_5KaroundTSS	DBTMEE Gene Entrez Total_mC_levels Number_of_mCs Averaged_Methylation_level 2004636 (v2.0) Chuk 12675 81.9176 147 55.73
SPR_Methy_Kobayashi_2KaroundTSS	DBTMEE Gene Entrez Total_mC_levels Number_of_mCs Averaged_Methylation_level 2004636 (v2.0) Chuk 12675 17.0394 79 21.57
SOLiD_OocyteTo4C_FPKM_gene_guided	N/A
SOLiD_Illumina_Oo_1C_Sperm_FPKM_gene_guided	N/A
SOLiD_Partheno1C_FPKM_gene_guided	N/A
SOLiD_Illumina_Oo_p1C_Sperm_FPKM_gene_guided	N/A
SOLiD_Partheno4C_FPKM_gene_guided	N/A
Illumina_Oo_2C_FPKM_gene_guided	N/A
SOLiD_SC_Oo_REPLICA_FPKM_gene_guided	N/A
NIA60mer	DBTMEE Array_Feature_Number Oligo_Parent_Clone Unigene Gene Entrez U_Cluster NAP_Cluster Gene_U/NAP TIGR SwissProt EST Oo 1C 2C 4C 8C Morula Blastocyst 5168 AF009225.1 CHUK CHUK 1.9088 2.3329 2.2327 2.3126 2.0881 2.1621 2.1507
MOE430	N/A
Agilent44K	N/A
Proteome	N/A