DBTMEE:2017706
Gene | Ptpn2 |
Synonyms | Ptpt TC-PTP |
Description | protein tyrosine phosphatase, non-receptor type 2 |
Locus | NM_001127177 UCSC: chr18:67825155-67884275(-) OLP: chr18:67825155-67884275(-) NM_008977 UCSC: chr18:67825155-67884275(-) OLP: chr18:67825155-67884275(-)
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DB links |

Entrez 19255 MGI 97806 Ensembl ENSMUSG00000024539 Vega OTTMUSG00000029831
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Feature | protein-coding |
GO_BP |
-
 32 Terms
protein dephosphorylation (GO:0006470)
negative regulation of cell proliferation (GO:0008285)
insulin receptor signaling pathway (GO:0008286)
negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)
negative regulation of lipid storage (GO:0010888)
dephosphorylation (GO:0016311)
B cell differentiation (GO:0030183)
T cell differentiation (GO:0030217)
erythrocyte differentiation (GO:0030218)
peptidyl-tyrosine dephosphorylation (GO:0035335)
negative regulation of epidermal growth factor receptor signaling pathway (GO:0042059)
negative regulation of tyrosine phosphorylation of Stat3 protein (GO:0042518)
negative regulation of tyrosine phosphorylation of Stat5 protein (GO:0042524)
negative regulation of tyrosine phosphorylation of Stat6 protein (GO:0042527)
glucose homeostasis (GO:0042593)
negative regulation of macrophage differentiation (GO:0045650)
positive regulation of gluconeogenesis (GO:0045722)
negative regulation of insulin receptor signaling pathway (GO:0046627)
negative regulation of inflammatory response (GO:0050728)
negative regulation of T cell receptor signaling pathway (GO:0050860)
negative regulation of chemotaxis (GO:0050922)
negative regulation of interferon-gamma-mediated signaling pathway (GO:0060336)
negative regulation of type I interferon-mediated signaling pathway (GO:0060339)
negative regulation of interleukin-6-mediated signaling pathway (GO:0070104)
negative regulation of ERK1 and ERK2 cascade (GO:0070373)
regulation of hepatocyte growth factor receptor signaling pathway (GO:1902202)
negative regulation of interleukin-2-mediated signaling pathway (GO:1902206)
negative regulation of prolactin signaling pathway (GO:1902212)
negative regulation of interleukin-4-mediated signaling pathway (GO:1902215)
negative regulation of macrophage colony-stimulating factor signaling pathway (GO:1902227)
negative regulation of positive thymic T cell selection (GO:1902233)
negative regulation of platelet-derived growth factor receptor-beta signaling pathway (GO:2000587)
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GO_MF |
-
 10 Terms
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GO_CC |
-
 6 Terms
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KEGG | |
Ver2_FPKM |
DBTMEE | Gene | RefSeq | Entrez | SPR_FPKM | Oo_FPKM | 1C_FPKM | 2C_FPKM | 4C_FPKM | ESC_FPKM | MEF_FPKM | p1C_FPKM | p4C_FPKM | iPSC_FPKM |
2017706 (v2.0) | Ptpn2 | NM_001127177,NM_008977 | 19255
| 6.50942 | 50.2786 | 52.8924 | 127.602 | 115.482 | 14.8885 | 18.4344 | 46.3804 | 108.995 | 17.4262 |
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SPR_Histone_Erkek_5KaroundTSS |
DBTMEE | Gene | Entrez | H3.3_1_ChIP/Input | H3.3_1(Enrich; log2) | H3.3_2_ChIP/Input | H3.3_2(Enrich; log2) | H3K4me3_1_ChIP/Input | H3K4me3_1(Enrich; log2) | H3K4me3_2_ChIP/Input | H3K4me3_2(Enrich; log2) | H3K27me3_1_ChIP/Input | H3K27me3_1(Enrich; log2) | H3K27me3_2_ChIP/Input | H3K27me3_2(Enrich; log2) |
2017706 (v2.0) | Ptpn2 | 19255
| 720/405 | 0.3166 | 478/405 | 0.1226 | 186/405 | 2.4436 | 551/405 | 1.7691 | 44/405 | -1.1269 | 305/405 | -1.0049 |
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SPR_Histone_Erkek_2KaroundTSS |
DBTMEE | Gene | Entrez | H3.3_1_ChIP/Input | H3.3_1(Enrich; log2) | H3.3_2_ChIP/Input | H3.3_2(Enrich; log2) | H3K4me3_1_ChIP/Input | H3K4me3_1(Enrich; log2) | H3K4me3_2_ChIP/Input | H3K4me3_2(Enrich; log2) | H3K27me3_1_ChIP/Input | H3K27me3_1(Enrich; log2) | H3K27me3_2_ChIP/Input | H3K27me3_2(Enrich; log2) |
2017706 (v2.0) | Ptpn2 | 19255
| 391/172 | 0.6688 | 248/172 | 0.4097 | 174/172 | 3.5277 | 519/172 | 2.9064 | 8/172 | -2.2331 | 87/172 | -1.5661 |
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SPR_Methy_Kobayashi_5KaroundTSS |
DBTMEE | Gene | Entrez | Total_mC_levels | Number_of_mCs | Averaged_Methylation_level |
2017706 (v2.0) | Ptpn2 | 19255
| 49.2002 | 124 | 39.68 |
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SPR_Methy_Kobayashi_2KaroundTSS |
DBTMEE | Gene | Entrez | Total_mC_levels | Number_of_mCs | Averaged_Methylation_level |
2017706 (v2.0) | Ptpn2 | 19255
| 16.4406 | 85 | 19.34 |
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SOLiD_OocyteTo4C_FPKM_gene_guided |
N/A |
SOLiD_Illumina_Oo_1C_Sperm_FPKM_gene_guided |
N/A |
SOLiD_Partheno1C_FPKM_gene_guided |
N/A |
SOLiD_Illumina_Oo_p1C_Sperm_FPKM_gene_guided |
N/A |
SOLiD_Partheno4C_FPKM_gene_guided |
N/A |
Illumina_Oo_2C_FPKM_gene_guided |
N/A |
SOLiD_SC_Oo_REPLICA_FPKM_gene_guided |
N/A |
NIA60mer |
DBTMEE | Array_Feature_Number | Oligo_Parent_Clone | Unigene | Gene | Entrez | U_Cluster | NAP_Cluster | Gene_U/NAP | TIGR | SwissProt | EST | Oo | 1C | 2C | 4C | 8C | Morula | Blastocyst |
0017200 (v1.0) | 12702 | H3150B11-5 | | Ptpn2 | 19255
| U038523 | NAP016461-001 | Ptpn2; | TC926014,TC859933 | Q06180 | U,F,2 | 2.5277 | 2.3711 | 2.4691 | 2.5884 | 2.1944 | 2.2535 | 2.0083 |
0017200 (v1.0) | 12986 | H3156C04-3 | Mm.985 | Ptpn2 | 19255
| U038523 | NAP017755-001 | Ptpn2; | TC859933 | Q06180 | U,F,2 | 2.5934 | 2.5835 | 2.7709 | 3.0831 | 2.6372 | 2.6974 | 2.4993 |
0017200 (v1.0) | 19448 | L0274A03-3 | Mm.985 | Ptpn2 | 19255
| U038523 | NAP016461-001 | Ptpn2; | TC926016,TC926014 | Q06180 | U,F,2 | 4.1182 | 4.0774 | 4.0142 | 4.2911 | 3.8812 | 3.8027 | 3.4044 |
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MOE430 |
N/A |
Agilent44K |
N/A |
Proteome |
N/A |