DBTMEE
Database of Transcriptome in Mouse Early Embryos


Gene Search:

DBTMEE:0010024
GeneHif1a
SynonymsbHLHe78
HIF-1alpha
HIF1alpha
MOP1
Desc.hypoxia inducible factor 1, alpha subunit
LocusNM_010431 chr12:75008854-75048517(+)
DB links


Entrez 15251
MGI 106918
Ensembl ENSMUSG00000021109
Vega OTTMUSG00000019740
Featureprotein-coding
GO(BP)
  •   70 Terms
      angiogenesis (GO:0001525)
      blood vessel development (GO:0001568)
      response to hypoxia (GO:0001666)
      neural crest cell migration (GO:0001755)
      epithelial to mesenchymal transition (GO:0001837)
      embryonic placenta development (GO:0001892)
      B-1 B cell homeostasis (GO:0001922)
      vasculature development (GO:0001944)
      heart looping (GO:0001947)
      positive regulation of neuroblast proliferation (GO:0002052)
      connective tissue replacement involved in inflammatory response wound healing (GO:0002248)
      outflow tract morphogenesis (GO:0003151)
      cardiac ventricle morphogenesis (GO:0003208)
      lactate metabolic process (GO:0006089)
      regulation of glycolysis (GO:0006110)
      transcription, DNA-dependent (GO:0006351)
      regulation of transcription, DNA-dependent (GO:0006355)
      cellular iron ion homeostasis (GO:0006879)
      signal transduction (GO:0007165)
      lactation (GO:0007595)
      positive regulation of cell proliferation (GO:0008284)
      visual learning (GO:0008542)
      regulation of gene expression (GO:0010468)
      vascular endothelial growth factor production (GO:0010573)
      positive regulation vascular endothelial growth factor production (GO:0010575)
      positive regulation of epithelial cell migration (GO:0010634)
      positive regulation of receptor biosynthetic process (GO:0010870)
      response to muscle activity (GO:0014850)
      axon transport of mitochondrion (GO:0019896)
      neural fold elevation formation (GO:0021502)
      cerebral cortex development (GO:0021987)
      cell differentiation (GO:0030154)
      negative regulation of bone mineralization (GO:0030502)
      positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949)
      negative regulation of TOR signaling cascade (GO:0032007)
      oxygen homeostasis (GO:0032364)
      regulation of transforming growth factor beta2 production (GO:0032909)
      collagen metabolic process (GO:0032963)
      negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)
      embryonic hemopoiesis (GO:0035162)
      positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0035774)
      regulation of cell proliferation (GO:0042127)
      hemoglobin biosynthetic process (GO:0042541)
      glucose homeostasis (GO:0042593)
      regulation of apoptotic process (GO:0042981)
      positive regulation of apoptotic process (GO:0043065)
      negative regulation of apoptotic process (GO:0043066)
      negative regulation of neuron apoptotic process (GO:0043524)
      regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043619)
      positive regulation of erythrocyte differentiation (GO:0045648)
      positive regulation of transcription, DNA-dependent (GO:0045893)
      negative regulation of vasoconstriction (GO:0045906)
      negative regulation of growth (GO:0045926)
      positive regulation of transcription from RNA polymerase II promoter (GO:0045944)
      muscle cell homeostasis (GO:0046716)
      positive regulation of hormone biosynthetic process (GO:0046886)
      blood vessel morphogenesis (GO:0048514)
      digestive tract morphogenesis (GO:0048546)
      positive regulation of smooth muscle cell proliferation (GO:0048661)
      regulation of catalytic activity (GO:0050790)
      cartilage development (GO:0051216)
      elastin metabolic process (GO:0051541)
      intestinal epithelial cell maturation (GO:0060574)
      epithelial cell differentiation involved in mammary gland alveolus development (GO:0061030)
      retina vasculature development in camera-type eye (GO:0061298)
      positive regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061419)
      cellular response to hypoxia (GO:0071456)
      dopaminergic neuron differentiation (GO:0071542)
      negative regulation of mesenchymal cell apoptotic process (GO:2001054)
      regulation of RNA biosynthetic process (GO:2001141)
GO(MF)
  •   19 Terms
      protein binding transcription factor activity (GO:0000988)
      RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (GO:0001077)
      DNA binding (GO:0003677)
      sequence-specific DNA binding transcription factor activity (GO:0003700)
      RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity (GO:0003705)
      signal transducer activity (GO:0004871)
      protein binding (GO:0005515)
      transcription factor binding (GO:0008134)
      enzyme binding (GO:0019899)
      protein kinase binding (GO:0019901)
      ubiquitin protein ligase binding (GO:0031625)
      protein complex binding (GO:0032403)
      histone acetyltransferase binding (GO:0035035)
      histone deacetylase binding (GO:0042826)
      sequence-specific DNA binding (GO:0043565)
      transcription regulatory region DNA binding (GO:0044212)
      protein heterodimerization activity (GO:0046982)
      protein dimerization activity (GO:0046983)
      Hsp90 protein binding (GO:0051879)
GO(CC)
KEGG
Ver2_FPKM
DBTMEEGeneRefSeqEntrezSPR_FPKMOo_FPKM1C_FPKM2C_FPKM4C_FPKMESC_FPKMMEF_FPKMp1C_FPKMp4C_FPKMiPSC_FPKM
2009905
(v2.0)
Hif1aNM_01043115251
11.7934122.46570.936411.53836.9352517.604942.693746.0299.7280115.2242
SOLiD_Cluster_gene_guided
DBTMEEGeneEntrezClusterCorrelation
0010024
(v1.0)
Hif1a15251
Maternal RNA0.95215
SPR_Histone_Erkek_+-5KfromTSS
DBTMEEGeneEntrezH3.3_1
(ChIP/Input)
H3.3_1
(Enrich; log2)
H3.3_2
(ChIP/Input)
H3.3_2
(Enrich; log2)
H3K4me3_1
(ChIP/Input)
H3K4me3_1
(Enrich; log2)
H3K4me3_2
(ChIP/Input)
H3K4me3_2
(Enrich; log2)
H3K27me3_1
(ChIP/Input)
H3K27me3_1
(Enrich; log2)
H3K27me3_2
(ChIP/Input)
H3K27me3_2
(Enrich; log2)
2009905
(v2.0)
Hif1a15251
723/3670.4643479/3670.2674137/3672.143327/3671.159352/367-0.7502341/367-0.7029
SPR_Histone_Erkek_+-2KfromTSS
DBTMEEGeneEntrezH3.3_1
(ChIP/Input)
H3.3_1
(Enrich; log2)
H3.3_2
(ChIP/Input)
H3.3_2
(Enrich; log2)
H3K4me3_1
(ChIP/Input)
H3K4me3_1
(Enrich; log2)
H3K4me3_2
(ChIP/Input)
H3K4me3_2
(Enrich; log2)
H3K27me3_1
(ChIP/Input)
H3K27me3_1
(Enrich; log2)
H3K27me3_2
(ChIP/Input)
H3K27me3_2
(Enrich; log2)
2009905
(v2.0)
Hif1a15251
420/1620.8576238/1620.4364130/1623.1904285/1622.129110/162-1.8592117/162-1.0592
SPR_Methy_Kobayashi_+-5KfromTSS
DBTMEEGeneEntrezTotal_mC_levelsNumber_of_mCsAveraged_Methylation_level(%)
2009905
(v2.0)
Hif1a15251
38.399512830
SPR_Methy_Kobayashi_+-2KfromTSS
DBTMEEGeneEntrezTotal_mC_levelsNumber_of_mCsAveraged_Methylation_level(%)
2009905
(v2.0)
Hif1a15251
9.3757979.67
SOLiD_Oo-4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM1C_FPKM2C_FPKM4C_FPKMMEF_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
127.24448.84768.584164.8221830.1928
SOLiD_NMNR_Oo-4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM1C_FPKM2C_FPKM4C_FPKMMEF_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
427.957169.21930.198915.535114.871
SOLiD_Illumina_Oo-1C-Sperm_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKMSPR_FPKM1C_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
133.0454.3129753.2938
SOLiD_Partheno1C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM1C_FPKMp1C_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
129.86548.357234.0253
SOLiD_NMNR_Partheno1C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrez1C_FPKMp1C_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
577.603386.833
SOLiD_Illumina_Oo-p1C-Sperm_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKMSPR_FPKMp1C_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
133.1224.2538937.3178
SOLiD_Partheno4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrez2C_FPKM4C_FPKMp4C_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
7.947594.656016.77715
SOLiD_NMNR_Partheno4C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrez4C_FPKMp4C_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
43.93440.4461
Illumina_Oo-2C_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_FPKM2C_FPKM
0010024
(v1.0)
Hif1aNM_01043115251
94.30537.41107
SOLiD_SC_Oo_REPLICA_FPKM_gene_guided
DBTMEEGeneRefSeqEntrezOo_1_1Oo_2_1
0010024
(v1.0)
Hif1aNM_01043115251
11.323131.5467
NIA60mer
DBTMEEArray Feature NumberOligo Parent CloneUnigeneGeneEntrezU_ClusterNAP_ClusterGene_U/NAPTIGRSwissProtESTOo1C2C4C8CMorulaBlastocyst
0010024
(v1.0)
975C0170D01-3Mm.3879Hif1a15251
U014085NAP000046-003Hif1a;TC927036,TC852944Q61221U,F,23.75843.6673.10972.90092.60392.89392.9287
MOE430
DBTMEEProbe_IDUnigeneGeneRefSeqEntrezOo1C2C8CBlastocyst
0010024
(v1.0)
1427418_a_atMm.446610Hif1a15251
1447.72140.025333.4750293.775
0010024
(v1.0)
1416035_atMm.446610Hif1a15251
448.675478.02500100.825
Agilent44K
DBTMEEProbe_IDGeneAcc.EntrezOo1_x-foldOo1_p-value (t-test)Oo1_FlagOo2_x-foldOo2_p-value (t-test)Oo2_Flag
0010024
(v1.0)
A_51_P387608Hif1aNM_01043115251
11P0.6440.146P
Proteome N/A