DBTMEE
Database of Transcriptome in Mouse Early Embryos


Gene Search:

DBTMEE:2019375
GeneSirt1
SynonymsSir2
Sir2alpha
Descriptionsirtuin 1
LocusNM_019812 UCSC: chr10:62781753-62801780(-) OLP: chr10:62781753-62801780(-)
NM_001159589 UCSC: chr10:62781753-62801783(-) OLP: chr10:62781753-62801783(-)
DB links


Entrez 93759
MGI 2135607
Ensembl ENSMUSG00000020063
Vega OTTMUSG00000030914
Featureprotein-coding
GO_BP
  •   90 Terms
      single strand break repair (GO:0000012)
      negative regulation of transcription from RNA polymerase II promoter (GO:0000122)
      chromatin silencing at rDNA (GO:0000183)
      pyrimidine dimer repair by nucleotide-excision repair (GO:0000720)
      DNA synthesis involved in DNA repair (GO:0000731)
      angiogenesis (GO:0001525)
      ovulation from ovarian follicle (GO:0001542)
      cellular glucose homeostasis (GO:0001678)
      positive regulation of protein phosphorylation (GO:0001934)
      positive regulation of adaptive immune response (GO:0002821)
      chromatin organization (GO:0006325)
      establishment of chromatin silencing (GO:0006343)
      maintenance of chromatin silencing (GO:0006344)
      transcription, DNA-templated (GO:0006351)
      regulation of transcription, DNA-templated (GO:0006355)
      rRNA processing (GO:0006364)
      protein deacetylation (GO:0006476)
      triglyceride mobilization (GO:0006642)
      apoptotic process (GO:0006915)
      cellular response to DNA damage stimulus (GO:0006974)
      response to oxidative stress (GO:0006979)
      multicellular organismal development (GO:0007275)
      spermatogenesis (GO:0007283)
      regulation of mitotic cell cycle (GO:0007346)
      muscle organ development (GO:0007517)
      positive regulation of cell proliferation (GO:0008284)
      intrinsic apoptotic signaling pathway in response to DNA damage (GO:0008630)
      cellular response to starvation (GO:0009267)
      positive regulation of cholesterol efflux (GO:0010875)
      regulation of glucose metabolic process (GO:0010906)
      positive regulation of macroautophagy (GO:0016239)
      protein ubiquitination (GO:0016567)
      histone deacetylation (GO:0016575)
      peptidyl-lysine acetylation (GO:0018394)
      cell differentiation (GO:0030154)
      negative regulation of cell growth (GO:0030308)
      negative regulation of transforming growth factor beta receptor signaling pathway (GO:0030512)
      negative regulation of prostaglandin biosynthetic process (GO:0031393)
      protein destabilization (GO:0031648)
      positive regulation of chromatin silencing (GO:0031937)
      negative regulation of TOR signaling (GO:0032007)
      regulation of endodeoxyribonuclease activity (GO:0032071)
      negative regulation of NF-kappaB transcription factor activity (GO:0032088)
      response to insulin (GO:0032868)
      regulation of protein import into nucleus, translocation (GO:0033158)
      regulation of smooth muscle cell apoptotic process (GO:0034391)
      peptidyl-lysine deacetylation (GO:0034983)
      cellular triglyceride homeostasis (GO:0035356)
      regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)
      regulation of cell proliferation (GO:0042127)
      negative regulation of phosphorylation (GO:0042326)
      response to hydrogen peroxide (GO:0042542)
      cholesterol homeostasis (GO:0042632)
      intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)
      positive regulation of apoptotic process (GO:0043065)
      negative regulation of apoptotic process (GO:0043066)
      negative regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043124)
      proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)
      positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043280)
      negative regulation of sequence-specific DNA binding transcription factor activity (GO:0043433)
      negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)
      positive regulation of MHC class II biosynthetic process (GO:0045348)
      negative regulation of fat cell differentiation (GO:0045599)
      positive regulation of DNA repair (GO:0045739)
      negative regulation of transcription, DNA-templated (GO:0045892)
      positive regulation of transcription from RNA polymerase II promoter (GO:0045944)
      positive regulation of insulin receptor signaling pathway (GO:0046628)
      white fat cell differentiation (GO:0050872)
      negative regulation of helicase activity (GO:0051097)
      positive regulation of histone H3-K9 methylation (GO:0051574)
      negative regulation of protein kinase B signaling (GO:0051898)
      fatty acid homeostasis (GO:0055089)
      negative regulation of androgen receptor signaling pathway (GO:0060766)
      cellular response to hydrogen peroxide (GO:0070301)
      regulation of bile acid biosynthetic process (GO:0070857)
      histone H3 deacetylation (GO:0070932)
      cellular response to tumor necrosis factor (GO:0071356)
      cellular response to hypoxia (GO:0071456)
      cellular response to ionizing radiation (GO:0071479)
      negative regulation of neuron death (GO:1901215)
      negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902166)
      negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress (GO:1902176)
      positive regulation of macrophage apoptotic process (GO:2000111)
      negative regulation of cAMP-dependent protein kinase activity (GO:2000480)
      positive regulation of cAMP-dependent protein kinase activity (GO:2000481)
      negative regulation of cellular response to testosterone stimulus (GO:2000655)
      negative regulation of peptidyl-lysine acetylation (GO:2000757)
      negative regulation of cellular senescence (GO:2000773)
      positive regulation of cellular senescence (GO:2000774)
      regulation of RNA biosynthetic process (GO:2001141)
GO_MF
GO_CC
KEGG
Ver2_FPKM
DBTMEEGeneRefSeqEntrezSPR_FPKMOo_FPKM1C_FPKM2C_FPKM4C_FPKMESC_FPKMMEF_FPKMp1C_FPKMp4C_FPKMiPSC_FPKM
2019375
(v2.0)		Sirt1NM_001159589,NM_01981293759
2.614917.234127.1537105.388103.94118.46998.2551817.7596101.37117.8308
SPR_Histone_Erkek_5KaroundTSS
DBTMEEGeneEntrezH3.3_1_ChIP/InputH3.3_1(Enrich; log2)H3.3_2_ChIP/InputH3.3_2(Enrich; log2)H3K4me3_1_ChIP/InputH3K4me3_1(Enrich; log2)H3K4me3_2_ChIP/InputH3K4me3_2(Enrich; log2)H3K27me3_1_ChIP/InputH3K27me3_1(Enrich; log2)H3K27me3_2_ChIP/InputH3K27me3_2(Enrich; log2)
2019375
(v2.0)		Sirt193759
672/3780.3165439/3780.0994180/3782.4931463/3781.617539/378-1.1983313/378-0.8684
SPR_Histone_Erkek_2KaroundTSS
DBTMEEGeneEntrezH3.3_1_ChIP/InputH3.3_1(Enrich; log2)H3.3_2_ChIP/InputH3.3_2(Enrich; log2)H3K4me3_1_ChIP/InputH3K4me3_1(Enrich; log2)H3K4me3_2_ChIP/InputH3K4me3_2(Enrich; log2)H3K27me3_1_ChIP/InputH3K27me3_1(Enrich; log2)H3K27me3_2_ChIP/InputH3K27me3_2(Enrich; log2)
2019375
(v2.0)		Sirt193759
339/1540.6223199/1540.2521161/1543.5647402/1542.695814/154-1.3406111/154-1.0615
SPR_Methy_Kobayashi_5KaroundTSS
DBTMEEGeneEntrezTotal_mC_levelsNumber_of_mCsAveraged_Methylation_level
2019375
(v2.0)		Sirt193759
54.924413740.09
SPR_Methy_Kobayashi_2KaroundTSS
DBTMEEGeneEntrezTotal_mC_levelsNumber_of_mCsAveraged_Methylation_level
2019375
(v2.0)		Sirt193759
15.74189516.57
SOLiD_OocyteTo4C_FPKM_gene_guided N/A
SOLiD_Illumina_Oo_1C_Sperm_FPKM_gene_guided N/A
SOLiD_Partheno1C_FPKM_gene_guided N/A
SOLiD_Illumina_Oo_p1C_Sperm_FPKM_gene_guided N/A
SOLiD_Partheno4C_FPKM_gene_guided N/A
Illumina_Oo_2C_FPKM_gene_guided N/A
SOLiD_SC_Oo_REPLICA_FPKM_gene_guided N/A
NIA60mer
DBTMEEArray_Feature_NumberOligo_Parent_CloneUnigeneGeneEntrezU_ClusterNAP_ClusterGene_U/NAPTIGRSwissProtESTOo1C2C4C8CMorulaBlastocyst
0018835
(v1.0)		5231AI322487.1Mm.12604Sirt193759
Sirt13.113.01563.30693.2133.12223.15393.0678
MOE430 N/A
Agilent44K N/A
Proteome N/A